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Antibiotics and AntifungalsMedical-Surgical Nursing-7th edition

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What super infections can develop on prolonged treatment with Cephalosporin class drugs?
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Fungal candida in the mouth (ulcers) or candida in the genital area.
Penicillins have a _______ structure.
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Beta Lactam
What generation is Keflex?
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1st generation
Penicillin, cephalosporin, and vancomycin all have a bactericidal effect by...
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inhibiting cell wall synthesis
What are the side effects and adverse reactions of aminoglycosides?
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Ototoxicity, nephrotoxicity, and super infection.
Chloroquine effects what lab test results?
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RBCs, hemoglobin, and hematocrit. (Blood dummy!)
Gentamicin Sulfate shouldn't be given to people with what conditions?
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Pregnancy and nursing; severe renal disease
A sulfonamide derivative for the treatment of 2nd and 3rd degree burns is _______.
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mafenide acetate (Sulfamyon)
The 3 major adverse effects related to antibacterial drugs are:
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allergies, organ toxicity, and super infections.
The MEC depends on what 4 things?
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Absorption, distribution, metabolism, and excretion.
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The newest aminoglycoside with a decreased occurrence of toxicity is _______, it's preg. cat. is _______.
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netilmicin; D
Amphotericin B is only administered via _______.
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IV
The broad spectrum penicillins like amoxicillin reduce the effectiveness of...
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oral contraceptives (ex. Amoxicillin and Augmentin)
What is the difference between 1st line and 2nd line antitubercular dugs?
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1st line are more effective and less toxic.
_______ sulfanomides are used to treat burns to prevent sepsis.
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Topical
If a patient is allergic to penicillin, you should be careful when they are prescribed what class of drugs?
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Cephalosporins
One major benefit of extended macrolides like Zithromax and Biaxin is...
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long half-lives (40-68 hours) requiring fewer doses.
What are the major concerns with Vancomycin?
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Ototoxicity and nephrotoxicity.
What are the 4 categories of penicillins?
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Basic, Broad Spectrum (amoxicillin and augmentin), Penicillin-Resistant, Extended Spectrum.
What are common uses for Vancomycin?
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Drug resistant s. aureus; cardiac surgical prophylaxis for people with penicillin allergies.
_______ vancomycin levels should be monitored.
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Serum vancomycin levels
  
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