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Antibiotics and AntifungalsMedical-Surgical Nursing-7th edition

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_______ vancomycin levels should be monitored.
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Serum vancomycin levels
What labs should be monitored closely for people on Amphotericin B?
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Urinary output, blood urea nitrogen, serum creatine levels.
The most significant side effect of Penicillins is...
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Allergic reaction; occurs in 5-10%.
Aminoglycosides are for _______ infections.
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serious infections
Which Penicillin is given by injection and IV, and is affective in achieving a therapeutic serum level?
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Penicillin G
Which Penicillin is effective against mild to moderate infections, including anthrax?
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Penicillin V
Penicillin taken orally _______ affected by the intake of food, whereas Amoxicillins _______ affected by food.
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Penicillins = affected by food, take 1 hour before or 2 hours after. Amoxicillins = are not affected by food.
Sulfanomides can cause _______ disorders if taken for prolonged periods.
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Blood disorders like hemolytic anemia, aplastic anemia and decreased WBC and platelet counts.
The tetracycline _______ should be taken with food to enhance absorbency.
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Doxycycline
Cephalosporin
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n/v/d, increased bleeding, nephrotoxicity to people with renal disorders, no alcohol, and no uricosuvic drugs.
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Aminoglycosides
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Ototoxicity, nephrotoxicity, super infection and increased coumadin effects.
Due to the adverse reaction of blood dyscrasias, fluoroquinolones are used only for treatment of serious infections with drugs like...
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Chloramphenicol
Clients with _______ are susceptible to Bactrim toxicity.
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HIV
_______ should not be taken with magnesium and aluminum preparations (antacids), milk products containing calcium or iron containing drugs because absorption is prevented.
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Tetracyclines
Fluoroquinolones are primarily prescribed to treat _______, but Levaquin treats _______.
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UTIs; LRI, renal, bone and joint infections
How is Augmentin different from Amoxicillin?
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Augmentin has a beta-lactamase inhibitor and amoxicillin, broad spectrum. Amoxicillin is easily deactivated by beta lactamases.
What aminoglycosides are the drug of choice for tularemia and bubonic pneumonic forms of plague?
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Streptomycin
What are the major things to watch for in a patient prescribed Amphotericin B?
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It is highly toxic, nephrotoxicity, electrolyte imbalance (decreased potassium and magnesium).
Aminoglycosides, tetracyclines and erythromycin are bacteriostatic or bactericidal by...
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inhibiting protein synthesis
The drug action of Coumadin can increase when taken simultaneously with _______.
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Aminoglycosides (like gentimicin)
Macrolides
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n/v/d, hepatotoxicity with acetaminophen, no clindamycin or lincomycin, interferes with anticonvulsants, anticoagulants and bronchodilators.
  
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