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Antibiotics and AntifungalsMedical-Surgical Nursing-7th edition

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Macrolides
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n/v/d, hepatotoxicity with acetaminophen, no clindamycin or lincomycin, interferes with anticonvulsants, anticoagulants and bronchodilators.
What are some adverse reactions of Levaquin?
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Stevens Johnson syndrome, encephalopathy, seizures, pseudomembranous colitis, dysrhythmias.
What are common side effects of azithromycin?
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Anorexia, n/v and diarrhea, tinnitus, abdominal cramps, pruritus (itchiness), and rash.
Macrolides are primarily _______ drugs.
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Bacteriostatic (*Can be bactericidal depending on pathogen and dose)
Antimalarial
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Cranial nerve VIII, hypotension, and psychosis.
Anti-Virals
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n/v/d, headache, tremors, itchy, increased bleeding, nephrotoxicity, neuropathy, and blood problems.
Antifungals
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Flush, fever/chills, n/v, hypotension, phlebitis, electrolyte imbalance, hypokalemia (Potassium) and hypomagnesaemia.
Sulfanomides
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Allergy, blood disorders, n/v/d, crystalluria, photo sensitivity, and cross-sensitivity.
Fluoroquinolones
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Stevens Johnson, n/v/d, tinnitus, photo sensitivity, and flush.
The drug frequently prescribed for clients with a hypersensitivity to penicillin is...
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azithromycin
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What are major side effects of Cephalosporins?
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GI disturbances (n/v, diarrhea), increased bleeding with large doses, nephrotoxicity with individuals with renal disorders, (Keflex), and super infection.
Coumadin plus these drugs = worries...
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aminoglycosides (Gentamicin)
What special instructions should be followed when taking tetracycline?
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Store out of light and extreme heat, it decomposes causing drug to become toxic. Check expiration date, can become toxic. Use sunscreen.
What drug discolors teeth of late term pregnant women and children under 8?
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Tetracyclines (Doxycycline)
Azithromycin peak levels may be reduced by _______ when taken at the same time.
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antacids
_______ can increase the effects of oral hypoglycemics.
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Levaquin
When levaquin is taken with _______, CNS reactions like seizures occur.
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NSAIDs
A drug that is a common substitute for penicillins is...
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Erythromycin
Sore throat, purpura and decreased WBC and platelet counts are a sign of a _______ reaction on _______.
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hematologic reaction; sulfanomides
What are the major differences between Diflucan and Amphotericin B?
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Amphotericin: polyene and IV only. Diflucan: azole and oral.
Drinking plenty of water while on sulfanomides prevents _______.
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crystalluria
  
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