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Hematology and CellsMedical-Surgical Nursing-7th edition

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Page 13
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All hemophilias have _______, _______, and _______ and an increased _______.
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Bruising; Purpura; Petchiae; increased PT time
Autosomal recessive disease, rare, deficiency in VWF that causes poor platelet quality...
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Von Willebrand disease.
What is Factor V Leiden?
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Genetic trait that results in resistance to protein C. 4 x's more likely to form clots. Caution with BC. Hyper coagulability.
_______ disease can cause a broad range of hemostasis disorders.
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Liver
This type of anemia is a complications of diseases like AIDS, RA, Lupus, Hepatitis, renal failure or malignancies.
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Anemia of chronic disease (Occurs in elderly. Normal ferritin, inefficient iron use).
What causes relative polycythemia?
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dehydration
The cytoplasm of erythrocytes contain _______.
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hemoglobin (Hb)
What happens in Peripheral Vascular Disease?
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Damage to the vessels from elevated blood sugar makes them unable to supply blood to distal areas (like the feet). Results in loss of feeling.
What are the nutritional requirements for hemoglobin synthesis?
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Proteins; amino acids; B2, B6, B12, Folic acid, Pantothenic acid, B3; C, E; Iron and Copper.
Hemophilia B (Christmas ) is factor _______ deficiency. It is less severe than A and accounts for _______% of hemophilias.
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factor 1X deficiency (9); 10%. X-linked recessive
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What is the major clotting factor in blood?
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Fibrinogen
Immune Thrombocytopenia Purpura (ITP) is a _______ mediated disease with a _______ cause.
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IgG mediated autoimmune; viral cause
What initiates DIC?
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endothelial damage
In a DIC patient, their FDP will _______ and the D-dimer levels will _______.
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Fibrin Degradation Product increases; D dimer (elevations of fibrin and fribinogen) increases
Pheochromocytoma - catecholamine producing tumor is a disorder of the _______.
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adrenal medulla
What are common causes of IDA (Iron Deficiency Anemia)?
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Decreased intake of iron, bleeding (heavy periods, colon cancer, ulcers)
(-) cytic refers to _______ and (-) chromic refers to _______.
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(-) cytic = size (micro, macro, normo) (-) chromic = hemoglobin content/weight
Erythrocytes are primarily responsible for _______.
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tissue oxygenation
The TIBC in a patient with sideroblastic anemia would be _______.
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low
The reduction in the total number of erythrocytes in the circulating blood or in the quality/quantity of hemoglobulin is called...
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anemia
What is TIBC and what does it tell us?
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It's the transferrin iron binding capacity; a low level (meaning iron is highly bound to transferrin) is normal; a high level indicates a problem.
  
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