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Hematology and CellsMedical-Surgical Nursing-7th edition

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TTAGG is called a...
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telomere
Mitosis occur in one...
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hour
The AB & C loci of MHC are found on all cells except... They are class _______.
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erythrocytes (RBC); class one
MHC consists of 4 closely linked loci on the short arm of chromosome _______.
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6
The start codon is _______.
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AUG which is methionine
What sends the signal to begin mitotic cell division?
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Proto-oncogens
The important genetic loci of the Rh system is _______.
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D
Rh - is _______, meaning dd is required for expression.
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recessive
Hemoglobin is an example of a _______ structure.
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Quaternary protein
This proto-oncogen goes to the nucleus of a cell and in response to GF/cyclin gives the signal for growth/division.
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RAS
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BRCA1 and BRCA2 are tumor suppressor genes linked to _______ cancer.
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Breast
A complete cell cycle occurs in _______ to _______ hours.
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24-Dec
G1, S & G2 phases all occur in what phase of the cell cycle?
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Interphase
Dystrophic Calcification
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The term used for the calcium build up in dead or dying cells.
What are the 2 ways chemical injury can occur?
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Direct toxicity to the cell; Formation of free radicals resulting in lipid peroxidation (lipid destruction).
Cellular self-digestion
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Auto-lysis
In apoptosis, the cells and genetic material _______.
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shrink (instead of swell as with an injury)
Skin, mucus membranes, decreased pH and body hairs are all components of...
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the 1st line of defense: anatomic barriers
_______ is increased WBC count.
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Leukocytosis
A myeloid cell can become what 4 different cell types?
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RBC, macrophage, platelets, granulocytes: eosinophils, neutrophils, basophils, mast cells.
What are the 7 steps of phagocytosis?
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1. chemotaxis (movement to site), 2. opsonization, recognition, adherence, 3. engulfment/ingestion, 4. phagosome formation, 5. fusion of the phagosome with lysosome, 6. destruction of foreign material, 7. residual body formed, discharge o
  
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