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Hematology and CellsMedical-Surgical Nursing-7th edition

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What are the 7 steps of phagocytosis?
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1. chemotaxis (movement to site), 2. opsonization, recognition, adherence, 3. engulfment/ingestion, 4. phagosome formation, 5. fusion of the phagosome with lysosome, 6. destruction of foreign material, 7. residual body formed, discharge o
What is the master watchman of cells?
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The tumor suppressor gene.
P53, RB1, BRCA1, BRCA2 and APC. Stand at check points and serve as watchmen. Monitor for mistakes. Repairs mistakes or initiates apoptosis.
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Tumor suppressor genes. If these aren't working, cancer develops.
RAS, ERBB and MYC. Normal genes that are working normally. They respond to growth factors and are responsible for cell growth and divisions...
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Proto-oncogenes
This WBC clears away debris and dead cells from a dissolving fibrin clot, aiding in wound healing...
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Macrophages
The portion of the antigen that binds with an antibody is called...
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an epitope
What are the 4 characteristics of antigens that enable them to produce an immune response?
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Size (needs to be large enough), foreignness, chemical complexity, quantity.
During the stress response, a person has increased _______ immunity and decreased _______ immunity.
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increased humoral, decreased cell mediated
_______ is the term used when an immunoglobulin is known to have a specificity for a certain antigen.
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Antibody
Foreignness, ability to produce an immune response is called...
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immunogenicity
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Emigration of phagocytes through the endothelial juctions that have retracted in response to inflammation is called...
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Diapedesis
The primary response is slow. After 5 days, Ig _______ is present.
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IgM
The secondary response is characterized by increased Ig______.
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IgG
Primary or secondary immune response? IgM and IgG present in equal amounts...
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1st (primary)
How many antigens can bind to one antibody?
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two
What WBC is the primary defense against parasites and turns inflammation off?
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Eosinophils
Natural immunity is _______ dependent.
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species
What part of the Ig structure binds to phagocytes and activates complement?
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crystalline fragment (Fc)
What part of the Ig structure binds antigens?
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The antigen binding fragment
Which antibody/ immunoglobulin arrives 1st during the primary immune response?
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IgM (also the largest)
What WBC can join together to eat larger particles?
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Macrophages
  
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