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Medication Administration BasicsMedical-Surgical Nursing-7th edition

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Low TI = _______ toxic, High TI = _______ toxic
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low = more toxic, high = less toxic
Free drugs are...
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Non-protein bound, available for a pharmacologic effect.
What type of drugs get thru the blood-brain barrier?
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Lipid soluble
In the Cytochrome P450 system, the majority of drug interactions occur with what enzyme?
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The CYP1
How does blood flow impact lipid soluble medications?
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Less blood flow: increase the dose or prolong duration (sinusitis). Increased blood flow: lower the dose or duration (strep throat, kidney infection, UTI). Abscesses: Increase dose, massage and heat help increase blood flow.
The biologic or physiologic response to a drug...
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Pharmacodynamics
A drug's affinity for particular tissues is it's...
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specificity
A drug's affinity for particular receptor's is it's...
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selectiveness
What drugs cannot be crushed or cut?
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Extended release and enteric coated.
Iron should never be taken with... Drinking _______ helps absorption.
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milk; drinking OJ
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The process of drug movement, absorption, distribution, metabolism and excretion...
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Pharmokinetics
Where does enteric coated drugs get metabolized?
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Small intestine
What type of lab should be ordered for a drug that's nephrotoxic?
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Creatine Clearance Lab
Alterations in _______ function interfere with oral medication distribution, absorption and excretion.
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GI
True or False? If a tablet comes prepackaged individually, you should remove the packaging and place the tablet in a medicine cup before entering the patient's room.
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False. The wrapper allows identification of the medication and dose bedside.
True or False? All medications for one patient can be put together in one medication cup.
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True, unless one of the medications requires a pre-administration assessment.
When applying a transdermal patch that is difficult to see, a nurse should?
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Apply a noticeable label to the patch
True or False? It is OK for a client to self administer prescribed nasal sprays.
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TRUE
To instill nasal drops to the ethmoid or sphenoid sinus, you should tilt the head _______.
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Backwards
To instill nasal drops to the frontal or maxillary sinus, you should tilt the head _______.
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Down and turned toward the side that is being treated.
When inserting a suppository into the anus, you should place it ______ inches within the anal vault in an adult and _______ inches in a child.
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When inserting a suppository into the anus, you should place it 4 inches within the anal vault in an adult and 2 inches in a child.
  
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