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Oncological emergencies and cancer medsMedical-Surgical Nursing-7th edition

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Page 6
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Neumega is administered via _______ and dosing should begin within _______ to _______ after completion of chemo.
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Sub Q; 6-24 hours of chemo
_______ is usually given with Adriamycin (doxorubicin) as a cytoprotective agent.
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Dexrazoxane (Zinecard)
CCS are _______ dependent and most effective in divided doses or by continuous infusion.
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schedule dependent
Doxorubicin/Adriamycin should be given through a _______, quickly running IV.
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large bore
The top 2 concerns for a patient on Doxorubicn/ Adriamycin are:
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cardiac damage and tissue damage (vesicant drug)
Cyclophosphamide (Cytoxan) is a/an _______ agent.
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alkylating
Proleukin is given via _______ and _______.
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IV or Sub Q
Renal and hepatic effects are dose dependent (interferon). They are usually detected by elevated...
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BUN, creatine, and transaminases; proteinuria is one external symptom
CAM
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Cyclophosphamide Doxorubicin (Adryamycin) Methotrexate
_______ are plant alkaloids and other compounds that are derived from natural products.
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Mitotic Inhibitor
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The duration, frequency and # of cycles of chemotherapy are based on...
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Type and size of tumor; whether it has metastasized; and condition of the patient.
_______ should be evaluated for a patient on EPO.
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Iron stores
A patient with mucositis/ stomatitis should avoid _______ and should use _______ during mouth care.
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avoid mouthwash with alcohol; brush with soft toothbrush
Nitrosoureas are an alkylating drug that is unique because...
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They cross the blood-brain barrier; useful in treatment of brain cancer
A person on Cyclophosphamide should have _______ done weekly.
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CBC, differential and platelet counts
What human, normal cells are generally impacted by anticancer drugs?
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*Rapidly, growing normal cells. Skin, hair, GI tract, mucous membranes, and vaginal cells.
Rituxan is an antibody directed against the _______ antigen found on normal and malignant _______.
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CD20 antigen; B lymphocytes; *The antibody is IgGI kappa.
A patient on Cyclophosphamide should be _______ to prevent hemorrhagic cystitis. _______ is usually prescribed as well as a cytoprotectant.
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well hydrated; MESNA = cytroprotectant (Cyclophosphamide/Cytoxan)
Doxorubin causes _______, so patients are limited to a life-time maximum dose of _______.
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causes cardiac toxicity; limited to 550mg; (Adriamycin)
Cyclophosphamide should be taken _______. The patient should urinate every _______ and drink _______ a day.
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should be taken in the morning; should urinate every 2-3 hours; drink 2-3 L a day
Cyclophosphamide is given by what routes of administration?
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Orally and IV.
  
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