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Oncological emergencies and cancer medsMedical-Surgical Nursing-7th edition

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Alkylating drugs, Nitrosources and Antitumor antibodies are _______ agents.
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Cell Cycle Nonspecific Agents (CCNS)
Cancer patients with neutropenia are at increased risk for _______.
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infection
What should be reported to the health care provider?
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Report: fever, chills, UR infections, and sore throat, temperature of 38.3 degrees C/100.9 degrees F.
Trastuzumag is an antibody (monoclonal) that helps kill breast cancer by blocking _______. (Herceptin)
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HER2 (Human Epidermal Growth Factor 2)
Vials of Neupogen should be used _______ and should be discarded within _______ when stored at room temp.
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Vials should be used once; Discard within 6 hours. *Don't shake vial.
Vehicles that deliver drugs to a cancer site are called _______.
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monoclonal antibodies
What factors guide the administration of chemotherapy?
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Type and extent of malignancy. Kind of chemotherapy given. Expected side effects. Amount of time normal cells need to recover.
______ drugs should be avoided 12 hours before infusion of rituximab.
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Antihypertensive
Roferon-A cannot be _______ or _______. Intron A can be _______ and is stable for _______ days.
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Roferon = no shaking or freezing; Intron = ok to shake, store for 30 days
Proleukin is recombinant _______, used in people with renal cell cancer or malignant melanoma.
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IL-2
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_______ agents are not true chemotherapy agents.
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Hormonal
Targeted cancer therapies work by...
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interfering with cancer cell growth and division
EPO can be administered via _______ or _______.
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IV or Sub Q
What tests should be done for a patient on IFN therapy?
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Baseline and periodic complete blood counts and liver function tests.
The liquid form of Roferon A comes in _______ million or _______ million IU/mL vials.
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3 or 18 million IU/mL
_______ may increase 5-FU toxicity.
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Metronidazole (treats trichomoniasis)
Neumega increases platelet counts within _______ to _______ after admin.
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5-9 days (*Platelets return to baseline within 14 days)
A patient on 5-FU should avoid _______.
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sunlight
_______ can cause shortness of breath and crackling in the lungs.
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Adriamycin/Doxorubicin
G-CSF's like Neulasta/ Filgrastim (Neupogen) are human _______.
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granulocyte stimulating factors
  
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