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Psychiatric BiologyPsychiatric Nursing: Contemporary Practice

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What type of disorders are challenge tests most often used to assess?
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Panic disorders
What drugs are used in a challenge test to assess panic disorders?
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Caffeine or lactate
What is the TRH stimulation test used to assess and how is it performed?
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It typically is used to evaluate for hypothyroidism, but has been used to assess for depression. TRH is administered and then blood levels are measured at intervals over a 3-4 hour time period.
What is the dexamethasone suppression test used to assess and how is it performed?
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It involves administering 1 mg of dexamethasone at 11:00 PM and then measuring cortisol levels at the time of administration, 7:00 AM, 4:00 PM, and 11:00 PM. Normal results would show a suppression of dexamethasone. Nonsuppression has been linked with d
TRH stimulation and dexamethasone suppression tests are examples of what category of tests?
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Endocrine stimulation tests
__________ is an assessment tool that measures electrical activity in the uppermost nerve layers of the cortex. Can be used to identify types of seizures, pinpoint locations of head injuries, assess efficacy of anti-depressants, or assess metabolic dysfu
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What medications can negatively impact the diagnostic value of an EEG?
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Benzodiazepines can increase the rapid and fast beta activity, lithium can increase theta activity, and if the EEG is a sleep deprivation assessment, caffeine or stimulants must be avoided because they can change EEG patterns.
What changes detected by polysomnography are considered biological markers for depression?
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Reduced delta sleep and shortened REM latency (the length of time it takes to enter the first REM episode)
What is polysomnography?
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A special procedure that involves recording an EEG throughout sleep, usually conducted in a sleep laboratory. Usually used to evaluate sleep disorders including sleep apnea, enuresis, or somnambulism.
________ measures changes in electrical activity in the brain in specific regions as a response to given stimuli. It is used to primarily in assessing demyelinating disorders like MS.
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Evoked Potentials (EP)
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_________ is an assessment tool that involves 20 electrode EEG to generate a computerized map of the brain?s electrical activity. Has been used to identify slowing of electrical activity in the frontal lobes of patients with schizophrenia.
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Brain Electrical Activity Mapping (BEAM)
________ examines the relationship among the immune system, the nervous system, endocrine system and thoughts, emotions and behaviors.
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Loss of this neurotransmitter causes memory losses and decreased intellectual functioning. Treated with Aricept.
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Too much of this neurotransmitter is the cause of cortical atrophy, also implicated in diseases like Huntington?s, Parkinson?s, and dementia. Neumenda is used to treat the overproduction.
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